Functions of galanin, spexin and kisspeptin in metabolism, mood and behaviour

EG Mills, C Izzi-Engbeaya, A Abbara… - Nature Reviews …, 2021 - nature.com
… mood disorders and abnormal eating behaviours, which results … ) promotes sexual partner
preference, processes sexually … (PVN)) galanin expression is increased by a high-fat diet and/…

Neuropeptidergic control of feeding: Focus on the galanin family of peptides

P Marcos, R Coveñas - International Journal of Molecular Sciences, 2021 - mdpi.com
… of action and physiological roles played by the GAL family of … GAL in feeding behaviour,
mainly related to fat intake [25]. … feeding behaviour: from voluntary access, natural preference/…

Blunted leptin sensitivity during hedonic overeating can be reinstated by activating galanin 2 receptors (Gal2R) in the lateral hypothalamus

E Leidmaa, M Gazea, AV Patchev, A Pissioti… - Acta …, 2020 - Wiley Online Library
… of the neurocircuitry that regulates feeding behaviour.35-37 It … 40 and that ghrelin increases
the reward salience of high-fat … In support of the latter view, we found that access to hedonic …

Neuropeptide modulation of addiction: Focus on galanin

SG Genders, KJ Scheller, E Djouma - Neuroscience & Biobehavioral …, 2020 - Elsevier
purpose of this review is to assess the role of major neuropeptides in reward-seeking behaviour,
with a focus on the galanin (… -3 KO mice reported an increased intake and preference for …

Mouse spexin:(II) functional role as a satiety factor inhibiting food intake by regulatory actions within the hypothalamus

MKH Wong, Y Chen, M He, C Lin, Z Bian… - Frontiers in …, 2021 - frontiersin.org
… expression in omental fat is sensitive to the feeding status, the … study implies that SPX and
galanin may form an intricate … is a 29-30 aa gut-brain peptide with a strong preference for …

Elimination of galanin synthesis in noradrenergic neurons reduces galanin in select brain areas and promotes active coping behaviors

RP Tillage, NR Sciolino, NW Plummer… - … Structure and Function, 2020 - Springer
… Sucrose preference test Mice were individually housed at … -suppressed feeding task, a
conflict test that pits a mouse’s … do not support this conclusion, as we saw no change in galanin

GAL3 receptor knockout mice exhibit an alcohol‐preferring phenotype

SG Genders, KJ Scheller, EJ Jaehne… - Addiction …, 2019 - Wiley Online Library
Galanin is a neuropeptide which mediates its effects via three G-… a similar preference for a
high fat diet over a low fat diet as … levels in GAL 3 -KO mice may feed the cycle between GAL …

Circulating galanin and galanin like peptide concentrations are correlated with increased triglyceride concentration in obese patients

P Fang, M Yu, X Gu, M Shi, Y Zhu, Z Zhang, P Bo - Clinica Chimica Acta, 2016 - Elsevier
… evidence supporting that GALP can regulate feeding behavior, … exercise and eating behavior,
without fat preference or fat aversion… The orexigenic effect of GALP on feeding behaviors is …

Anti-obesity effect of intranasal administration of galanin-like peptide (GALP) in obese mice

H Kageyama, K Shiba, S Hirako, N Wada… - Scientific reports, 2016 - nature.com
… of GALP on the feeding behavior of lean and obese mice. … and Zucker fatty rats, compared
with wild-type animals 5 . … The preference ratio was calculated as the intake of the drug-…

Time-restricted feeding prevents metabolic diseases through the regulation of galanin/GALR1 expression in the hypothalamus of mice

J Sun, Y She, P Fang, X Gu, Z Zhang - Eating and Weight Disorders …, 2022 - Springer
… studies suggest a critical role of hypothalamic galanin and its … we subjected mice to either
ad lib or TRF of a high-fat diet for 8 … feeding to 8 h of a rodent’s preferred nocturnal feeding time …